Application
LIN54 Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the LIN54 antibody detected the LIN54 protein (arrow).| Product Name | LIN54 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LIN54; CXCDC1; KIAA2037; Protein lin-54 homolog; CXC domain-containing protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CXCDC1 KIAA2037 |
|---|---|
| Alternative Names | LIN54 CXCDC1 KIAA2037 Protein lin-54 homolog CXC domain-containing protein 1 |
| Molecular Weight(MW) | 79494 Da |
| Function | Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner |
| Tissue Specificity | This LIN54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-599 amino acids from the C-terminal region of human LIN54. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 132660 |
|---|---|
| Nucleotide Accession | NP_001108479.1 NP_001108480.1 |
Application
LIN54 Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the LIN54 antibody detected the LIN54 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
