LLGL2; Lethal(2) giant larvae protein homolog 2; HGL
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
LLGL2 Lethal(2) giant larvae protein homolog 2 HGL
Molecular Weight(MW)
113448 Da
Function
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity
Tissue Specificity
This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LLGL2.
Cellular Localization
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells
Western blot analysis of anti-LLGL2 Pab in 293 cell line lysate (35ug/lane). LLGL2(arrow) was detected using the purified Pab (1:20 dilution).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.