Application
LOC388630 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the LOC388630 antibody detected the LOC388630 protein (arrow).| Product Name | LOC388630 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TIKI2 |
|---|---|
| Alternative Names | UPF0632 protein A |
| Molecular Weight(MW) | 57421 Da |
| Function | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation |
| Tissue Specificity | This LOC388630 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-426 amino acids from the C-terminal region of human LOC388630. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 388630 |
|---|---|
| Nucleotide Accession | NP_001181915.1 |
Application
LOC388630 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the LOC388630 antibody detected the LOC388630 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
