Application
LONP1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LONP1 antibody detected the LONP1 protein (arrow).| Product Name | LONP1 (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LONP1; PRSS15; Lon protease homolog, mitochondrial; LONHs; Lon protease-like protein; Mitochondrial ATP-dependent protease Lon; Serine protease 15 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PRSS15 |
|---|---|
| Alternative Names | LONP1 PRSS15 Lon protease homolog mitochondrial LONHs Lon protease-like protein Mitochondrial ATP-dependent protease Lon Serine protease 15 |
| Molecular Weight(MW) | 106489 Da |
| Function | ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single- stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site- specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein |
| Tissue Specificity | Duodenum, heart, lung and liver, but not thymus |
| Cellular Localization | Mitochondrion matrix. |
| Entrez Gene | 9361 |
|---|---|
| Nucleotide Accession | NP_004784.2 |
Application
LONP1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LONP1 antibody detected the LONP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
