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LRRC16A Antibody (C-term)

Catalog Number:OM237395
OM237395
Discount Price
OM237395-100ul
1~2 Week
100ul
OM237395-50ul
50ul
OM237395-20ul
20ul
1~2 Week
Product Profile
Product Name LRRC16A Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CARMIL, LRRC16
Alternative Names LRRC16A
CARMIL
LRRC16
Leucine-rich repeat-containing protein 16A
CARMIL homolog
Molecular Weight(MW) 151557 Da
Function Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity)
Tissue Specificity Expressed in lung, placenta, small intestine, liver, thymus, colon, skeletal muscle, heart and brain. Higher expression in kidney
Cellular Localization Cytoplasm. Note=Colocalized with F-actin in lamellipodia but not with F-actin in stress fibers
Database Links
Entrez Gene 55604
Nucleotide Accession NP_060110.4
Application

Application

LRRC16A Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the LRRC16A antibody detected the LRRC16A protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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