LRRC16A Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the LRRC16A antibody detected the LRRC16A protein (arrow).
LRRC16A CARMIL LRRC16 Leucine-rich repeat-containing protein 16A CARMIL homolog
Molecular Weight(MW)
151557 Da
Function
Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity)
Tissue Specificity
Expressed in lung, placenta, small intestine, liver, thymus, colon, skeletal muscle, heart and brain. Higher expression in kidney
Cellular Localization
Cytoplasm. Note=Colocalized with F-actin in lamellipodia but not with F-actin in stress fibers
LRRC16A Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the LRRC16A antibody detected the LRRC16A protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.