Rabbit polyclonal antibody to 3BP2 (SH3-domain binding protein 2)The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human 3BP2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
3BP2 antibody CRBM antibody CRPM antibody FLJ42079 antibody FLJ54978 antibody SH3BP2 antibody TNFAIP3 interacting protein 2 antibody Abl-SH3 binding protein 2 antibody SH3 domain-binding protein 2 antibody SH3-domain binding protein 2 antibody
Target
3BP2
Molecular Weight(MW)
62 kDa (note) (4)
Application
Application
Sample (30 ug of whole cell lysate) A: Hep G2 7.5% SDS PAGE diluted at 1:1000
Positive Control
A431 , HeLa , HepG2 , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.