Application
Western blot analysis using anti-4E-BP1 monoclonal antiobdy against truncated 4E-BP1 recombinant protein(1).Application
Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma(A), esophagus carcinoma tissue(B) and ovary tumor tissue©, showing cytoplasmic and membrane localization using anti-4E-BP1 antibody with DAB staining.| Product Name | 4E-BP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [11G12C11] to 4E-BP1This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to 4EBP1 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 11G12C11 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | BP-1 EIF4EBP1 4EBP1 PHAS-I |
|---|---|
| Target | 4E-BP1 |
Application
Western blot analysis using anti-4E-BP1 monoclonal antiobdy against truncated 4E-BP1 recombinant protein(1).
Application
Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma(A), esophagus carcinoma tissue(B) and ovary tumor tissue©, showing cytoplasmic and membrane localization using anti-4E-BP1 antibody with DAB staining.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
