Rabbit Polyclonal antibody to 5-HT1B receptorThe neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 5HT1B Receptor. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Dog, Cat, Pig, Rabbit, ChimpanzeeMouse (100%), Rat (100%), Dog (100%), Cat (100%), Pig (100%), Rabbit (100%), Chimpanzee (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)