Application
Western Blot: SR-1E Antibody [ - extracts from HeLa cells.| Product Name | 5-HT1E receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Serotonin receptor 1EThe members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1?7 (5HT1?7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| We recommend the following starting dilutions: Western Blot 1:500-1:1000. Optimal concentration should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | S31 3354 5HT 5HT1E 5-HT-1E 5-HT1E HTR1E 5 HT1E receptor 5HT1E receptor 5 HT1E 5 HT 1E |
|---|---|
| Target | Serotonin receptor 1E |
| Tissue Specificity | SR-1E (A127) detects endogenous levels of SR-1E protein. |
Application
Western Blot: SR-1E Antibody [ - extracts from HeLa cells.| Application Notes | We recommend the following starting dilutions: Western Blot 1:500-1:1000. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
