Application
Sample (30 µg of whole cell lysate) A: IMR32 5% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Product Name | ABL2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ABL2 (v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene))This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ABL2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Xenopus laevis, BovineMouse (99%), Rat (99%), Zebrafish (96%), Xenopus laevis (96%), Bovine (99%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ABLL antibody ARG antibody FLJ22224 antibody FLJ31718 antibody FLJ41441 antibody ABL2 antibody abelson-related gene protein antibody Abelson tyrosine-protein kinase 2 antibody tyrosine-protein kinase ARG antibody v-abl Abelson murine leukemia vira |
|---|---|
| Molecular Weight(MW) | 128 kDa (note) (8) |
| Tissue Specificity | Knockdown/Knockout validation was supported by references (PMID:27293031) |
| Cellular Localization | Cytoplasm , cytoskeleton |
Application
Sample (30 µg of whole cell lysate) A: IMR32 5% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Positive Control | IMR32 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
