Application
ACE antibody detects ACE protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 5 % SDS-PAGE, and the membrane was blotted with ACE antibody at a dilution of 1:500.| Product Name | ACE antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ACE (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1)This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ACE. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Pig, Rabbit, Chimpanzee, BovineHuman (100%), Rat (80%), Pig (83%), Rabbit (87%), Chimpanzee (99%), Bovine (82%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ACE1 antibody CD143 antibody DCP antibody DCP1 antibody MGC26566 antibody MVCD3 antibody ACE antibody dipeptidyl carboxypeptidase 1 antibody angiotensin-converting enzyme antibody carboxycathepsin antibody peptidase P antibody dipeptidyl carboxy |
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| Molecular Weight(MW) | 150 kDa (note) (3) |
| Cellular Localization | Angiotensin-converting enzyme , soluble form: Secreted , Cell membrane |
Application
ACE antibody detects ACE protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 5 % SDS-PAGE, and the membrane was blotted with ACE antibody at a dilution of 1:500.| Positive Control | mouse lung |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
