Rabbit Polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ACE2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Dog, Cat, Pig, Rhesus Monkey, BovineMouse (86%), Rat (86%), Dog (90%), Cat (88%), Pig (84%), Rhesus Monkey (98%), Bovine (85%)