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Acetyl CoA Carboxylase 1 antibody

Catalog Number:OM237964
OM237964
Discount Price
OM237964-100ul
1~2 Week
100ul
OM237964-50ul
50ul
OM237964-20ul
20ul
1~2 Week
Product Profile
Product Name Acetyl CoA Carboxylase 1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Acetyl CoA Carboxylase 1 (acetyl-CoA carboxylase alpha)Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Acetyl CoA Carboxylase 1. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouseRat
Predicted Reactivity Pig, Chicken, Sheep, Rhesus Monkey, BovinePig (94%), Chicken (83%), Sheep (94%), Rhesus Monkey (98%), Bovine (94%)
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms ACAC antibody
ACACA antibody
ACACAD antibody
ACC antibody
ACC1 antibody
ACCA antibody
Acetyl CoA Carboxylase 1 antibody
Acetyl CoA Carboxylase 1 antibody
acetyl-CoA carboxylase alpha antibody
Target Acetyl CoA Carboxylase 1
Molecular Weight(MW) 266 kDa (note) (5)
Cellular Localization Cytoplasm
Application

Application

Acetyl CoA Carboxylase 1 antibody detects Acetyl CoA Carboxylase 1 protein at cytoplasm in rat liver by immunohistochemical analysis. Sample: Paraffin-embedded rat liver. Acetyl CoA Carboxylase 1 antibody diluted at 1:500.

Application

Acetyl CoA Carboxylase 1 antibody detects Acetyl CoA Carboxylase 1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Acetyl CoA Carboxylase 1 protein stained by Acetyl CoA Carboxylase 1 antibody diluted at 1:500. Blue: Hoechst 33342 staining.

Application

Acetyl CoA Carboxylase 1 antibody detects Acetyl CoA Carboxylase 1 protein at cytoplasm in mouse cervix by immunohistochemical analysis. Sample: Paraffin-embedded mouse cervix. Acetyl CoA Carboxylase 1 antibody diluted at 1:500.

Application

Various whole cell extracts (30 µg) were separated by 5% SDS-PAGE, and the membrane was blotted with Acetyl CoA Carboxylase 1 antibody diluted at 1:1000.
Positive Control 293T , A431 , HeLa , HepG2
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
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