| Product Name | AChR beta 4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to AChR beta 4The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero) pentamers composed of homologous subunits. After binding acetylcholine, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Immunogen | Synthetic peptide derived from CHRNB4 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| We recommend the following starting dilutions: immunohistochemistry 1:50 to 1:500, Western Blot 1:200 to 1:2000. Optimal concentration should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | beta polypeptide2 (neuronal) Nicotinic Acetylcholine receptor beta4 nicotinic Cholinergic receptor EFNL3 neuronal nicotinic acetylcholine receptor bet beta 2 (neuronal) beta2 (neuronal) nAChRB2 CHRNB4 CHRNB2 beta polypeptide 2 (neuronal) 1143 |
|---|---|
| Target | AChR beta 4 |
| Tissue Specificity | Reacts specifically with human 56 kDa protein |
| Application Notes | We recommend the following starting dilutions: immunohistochemistry 1:50 to 1:500, Western Blot 1:200 to 1:2000. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Lyophilized Whole Rabbit antisera. |
