Rabbit Polyclonal antibody to AChR epsilonAcetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human AChR epsilon
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Guinea Pig: 84%; Mouse: 91%; Pig: 80%; Rat: 91%
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Synonyms
FCCMS CMS1E CMS2A ACHRE CHRNE SCCMS CMS1D
Target
AChR epsilon
Molecular Weight(MW)
55 KDa (note)
Application
Application
WB analysis of HepG2 cells using AChR epsilon antibody at 1.25μg/ml.
Positive Control
HepG2
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.