Application
WB analysis of K562 cell lysate using Acinus (splice variants L/S/S') antibody| Product Name | Acinus (spice variants L/S/S') antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Acinus (spice variants L/S/S')Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
| Immunogen | Peptide SRSTPVRDRGGRR corresponding to the C-terminal region of Acinus. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ACINUS ACIN1 ACN FSAP152 |
|---|---|
| Target | Acinus & spice variants L, S, S' |
| Tissue Specificity | This antibody recognizes a C-terminal region within three splice forms of Acinus, designated Acinus L, Acinus S and Acinus S'. |
Application
WB analysis of K562 cell lysate using Acinus (splice variants L/S/S') antibody| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered Saline containing 0.02% Sodium Azide |
