Application
Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE diluted at 1:1000Application
Immunohistochemical analysis of paraffin-embedded SAS xenograft, using ACMSD antibody at 1:100 dilution.Application
Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 10% SDS PAGE diluted at 1:1000| Product Name | ACMSD antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ACMSD (aminocarboxymuconate semialdehyde decarboxylase)The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ACMSD. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Zebrafish, BovineRat (88%), Zebrafish (86%), Bovine (93%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ACMSD antibody picolinate carboxylase antibody 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody aminocarboxymuconate semialdehyde decarboxylase antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa (note) (2) |
Application
Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded SAS xenograft, using ACMSD antibody at 1:100 dilution.
Application
Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 10% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 , H1299 , HeLa , Molt-4 , Raji , mouse brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
