| Product Name | Acrolein antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to AcroleinAcrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimer's disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein. |
| Immunogen | Acrolein carriers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA: Use at a dilution of 1/2000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Target | Acrolein |
|---|---|
| Tissue Specificity | Using a conjugate Acrolein Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds.Acrolein-BSA (ratio 1:1), Malondialdehyde-BSA (1:55), Glyoxal-BSA (1:> 50,000), Formaldehyde-BSA (1:> 50,000), Glutaraldehyde-BSA (1/> 50,000). Crossreactivity ratio is the Acrolein BSA concentration/unconjugated or conjugated analogs concentration at half displacement. |
| Application Notes | ELISA: Use at a dilution of 1/2000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: NoneConstituents: 40% Glycerol, PBS |
