Application
Immunofluorescence of TACE in HeLa cells with TACE antibody at 10 ug/mL.Application
Western blot analysis of TACE in HeLa and Jurkat whole cell lysate in the absence or presence of blocking peptide with TACE antibody at 0.5 ug/mL.Application
Immunocytochemistry of TACE in HeLa cells with TACE antibody at 10 ug/mL.| Product Name | ADAM17 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ADAM17This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008] |
| Immunogen | TACE antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TACE. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAFACSICC/IFWB |
| WB: 0.5 ug/ml. ICC: 10 ug/ml. IF: 10 ug/ml: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CSVP ADAM metallopeptidase domain 17 ADAM18 TACE NISBD CD156B |
|---|---|
| Target | ADAM17 |
| Tissue Specificity | 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated TACE. |
Application
Immunofluorescence of TACE in HeLa cells with TACE antibody at 10 ug/mL.
Application
Western blot analysis of TACE in HeLa and Jurkat whole cell lysate in the absence or presence of blocking peptide with TACE antibody at 0.5 ug/mL.
Application
Immunocytochemistry of TACE in HeLa cells with TACE antibody at 10 ug/mL.| Application Notes | WB: 0.5 ug/ml. ICC: 10 ug/ml. IF: 10 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
