Rabbit Polyclonal antibody to ADAM9 (ADAM metallopeptidase domain 9)This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ADAM9. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
HumanMouse
Predicted Reactivity
Rat, Dog, Chicken, BovineRat (92%), Dog (93%), Chicken (80%), Bovine (88%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MCMP MDC9 CORD9 Mltng ADAM metallopeptidase domain 9
Target
ADAM9
Molecular Weight(MW)
91 kDa (note)
Cellular Localization
Isoform 1: Cell membrane , Isoform 2: Secreted
Application
Application
Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ADAM9 antibody diluted at 1:1000.