Rabbit Polyclonal antibody to Adenylate kinase 2Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
Immunogen
Recombinant protein of human AK2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ADK2 AK 2 AK2 adenylate kinase 2
Target
Adenylate kinase 2
Application
Application
Western blot analysis of extracts of various cell lines, using AK2 antibody.
Application
Immunohistochemistry of paraffin-embedded human gastric cancer using AK2 antibody at dilution of 1:100 (x40 lens).