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ADSL antibody

Catalog Number:OM238464
OM238464
Discount Price
OM238464-100ul
1~2 Week
100ul
OM238464-50ul
50ul
OM238464-20ul
20ul
1~2 Week
Product Profile
Product Name ADSL antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to ADSL (adenylosuccinate lyase)Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human ADSL. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouse
Predicted Reactivity Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Chimpanzee, BovineRat (95%), Zebrafish (84%), Xenopus laevis (90%), Pig (97%), Chicken (91%), Chimpanzee (98%), Bovine (95%)
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms AMPS antibody, ASASE antibody, ASL antibody, ADSL antibody, adenylosuccinate lyase antibody, adenylosuccinase antibody
Target ADSL
Molecular Weight(MW) 55 kDa (note) (3)
Application

Application

Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE ASL antibody diluted at 1:1000

Application

ADSL antibody [N3C3] detects ADSL protein at cytosol on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. ADSL antibody [N3C3] dilution: 1:500.
Application Notes *Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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