Application
Western blot analysis on (A) C2C12, (B) PC-12, (C) HeLa, and (D) HepG2 cell lysates using anti-Type-1 Angiotensin II receptor RabMAb (cat. #).| Product Name | AGTR1 antibody [EPR3873] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [EPR3873] to AGTR1Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. Angiotensin II acts through at least two types of receptors. Type-1 Angiotensin II receptor is thought to mediate the major cardiovascular effects of angiotensin II. It may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related protein, denoted as Type-1b, existed; however, it is now believed that there is only one Type-1 Angiotensin II receptor in humans (1). |
| Immunogen | A synthetic peptide corresponding to residues on the N-terminus in human Type-1 Angiotensin II receptor was used as an immunogen. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | EPR3873 |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at 1:1,000 - 10,000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R |
|---|---|
| Target | AGTR1 |
Application
Western blot analysis on (A) C2C12, (B) PC-12, (C) HeLa, and (D) HepG2 cell lysates using anti-Type-1 Angiotensin II receptor RabMAb (cat. #).| Application Notes | For WB: Use at 1:1,000 - 10,000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
