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AICDA antibody

Catalog Number:OM238578
OM238578
Discount Price
OM238578-100ul
1~2 Week
100ul
OM238578-50ul
50ul
OM238578-20ul
20ul
1~2 Week
Product Profile
Product Name AICDA antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to AICDA (activation-induced cytidine deaminase)This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human AICDA. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Chicken, Chimpanzee, BovineMouse (93%), Rat (96%), Dog (97%), Chicken (91%), Chimpanzee (100%), Bovine (97%)
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms AID antibody, ARP2 antibody, CDA2 antibody, HIGM2 antibody, AICDA antibody, cytidine aminohydrolase antibody, activation-induced cytidine deaminase antibody, integrated into Burkitt's lymphoma cell line Ramos antibody
Molecular Weight(MW) 24 kDa (note) (3)
Application

Application

AICDA antibody detects AICDA protein at cytosol on SAS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SAS xenograft. AICDA antibody dilution: 1:500.

Application

Sample (30 µg of whole cell lysate) A: K562 B: THP-1 C: HL-60 12% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Application

AICDA antibody detects AICDA protein at cytoplasm by immunofluorescent analysis. Sample: Raji cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: AICDA protein stained by AICDA antibody diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm.
Application Notes *Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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