Rabbit Polyclonal antibody to AIMP1The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
Immunogen
AIMP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AIMP1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
WB: 0.5 - 1 ug/ml
Species Reactivity
MouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
AIMP1 antibody is mouse and rat reactive. At least two isoforms of AIMP1 are known to exist; this antibody will recognize both isoforms. AIMP1 antibody is predicted to not cross-react with AIMP2.
Application
Application
Immunohistochemistry of AIMP1 in mouse brain tissue with AIMP1 antibody at 5 ug/mL.
Application
Western blot analysis of AIMP1 in rat brain tissue lysate with AIMP1 antibody at (A) 0.5 and (B) 1 ug/ml.
Application Notes
WB: 0.5 - 1 ug/ml
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year.