Application
Western blot analysis of extracts from HeLa cells treated with Hu using AIRE (Phospho-Ser156) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | AIRE (phospho Ser156) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to AIRE (phospho Ser156)This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012] |
| Immunogen | Peptide sequence around phosphorylation site of Serine156 P-G-S(p)-Q-L) derived from Human AIRE. |
| Modification | p-Ser156 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | APS1 , APSI , autoimmune regulator , APECED , AIRE , PGA1 , AIRE1 |
|---|---|
| Target | AIRE (phospho Ser156) |
| Tissue Specificity | The antibody detects endogenous levels of AIRE only when phosphorylated at serine 156. |
Application
Western blot analysis of extracts from HeLa cells treated with Hu using AIRE (Phospho-Ser156) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
