Rabbit Polyclonal antibody to AKAP8L (A kinase (PRKA) anchor protein 8-like)Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
Immunogen
Recombinant protein encompassing a sequence within the center region of human AKAP8L. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIPWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Rhesus MonkeyMouse (94%), Rat (93%), Rhesus Monkey (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
DKFZp434L0650 antibody, HA95 antibody, HAP95 antibody, NAKAP antibody, NAKAP95 antibody, AKAP8L antibody, homologous to AKAP95 protein antibody, AKAP8-like protein antibody, neighbor of A kinase anchoring protein 95 antibody, A-kinase anchor protein 8-like
Molecular Weight(MW)
72 kDa (note) (2)
Tissue Specificity
Knockdown/Knockout validation was supported by references (PMID:26991010)
Application
Application
Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE diluted at 1:5000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.