Rabbit polyclonal antibody to AKR1B1This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
Immunogen
Recombinant protein of human AKR1B1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ALR2 , ALDR1 , aldo-keto reductase family 1, member B1 (aldose reductase) , AR , ADR
Target
AKR1B1
Molecular Weight(MW)
36 kDa (note)
Application
Application
WB analysis of extracts from various cell lines using AKR1B1 antibody.
Application
IHC-P analysis of human esophageal cancer using AKR1B1 antibody at a dilution of 1:200.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.