Rabbit polyclonal antibody to AKR1B1 (aldo-keto reductase family 1, member B1 (aldose reductase))This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Aldose Reductase. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Rat, Dog, Pig, Rabbit, Rhesus Monkey, BovineRat (89%), Dog (94%), Pig (91%), Rabbit (92%), Rhesus Monkey (97%), Bovine (88%)
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ADR antibody ALDR1 antibody ALR2 antibody AR antibody MGC1804 antibody AKR1B1 antibody aldehyde reductase 1 antibody aldose reductase antibody aldo-keto reductase family 1 member B1 antibody low Km aldose reductase antibody Lii5-2 CTCL tumor anti
Target
Aldose Reductase
Molecular Weight(MW)
36 kDa (note)
Cellular Localization
Cytoplasm
Positive Control
Target recombinant protein
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.