Application
Western blot analysis of extracts of various tissues, using ALDH2 antibody.Application
Immunofluorescence analysis of A549 cell using ALDH2 antibody.Application
Immunohistochemistry of paraffin-embedded human esophageal cancer using ALDH2 antibody at dilution of 1:100 (400x lens).Application
Immunohistochemistry of paraffin-embedded rat liver using ALDH2 antibody at dilution of 1:100 (400x lens).Application
Immunohistochemistry of paraffin-embedded rat kidney using ALDH2 antibody at dilution of 1:100 (400x lens).| Product Name | ALDH2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ALDH2This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011] |
| Immunogen | Recombinant protein of human ALDH2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IF,IHC,IHC-P,WB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200 | |
| Species Reactivity | Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ALDM , ALDH E2 , aldehyde dehydrogenase 2 family (mitochondrial) , ALDHI |
|---|---|
| Target | ALDH2 |
Application
Western blot analysis of extracts of various tissues, using ALDH2 antibody.
Application
Immunofluorescence analysis of A549 cell using ALDH2 antibody.
Application
Immunohistochemistry of paraffin-embedded human esophageal cancer using ALDH2 antibody at dilution of 1:100 (400x lens).
Application
Immunohistochemistry of paraffin-embedded rat liver using ALDH2 antibody at dilution of 1:100 (400x lens).
Application
Immunohistochemistry of paraffin-embedded rat kidney using ALDH2 antibody at dilution of 1:100 (400x lens).| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
