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ALDH2 antibody

Catalog Number:OM238837
OM238837
Discount Price
OM238837-100ul
1~2 Week
100ul
OM238837-50ul
50ul
1~2 Week
Product Profile
Product Name ALDH2 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [4G6A3] to ALDH2This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in
Immunogen The immunogen corresponding to a region within amino acids 317 and 517 of human ALDH2 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 4G6A3
Host Species Mouse
Tested Applications ELISAFACSICC/IFIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity HumanMouseRat
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms ALDM
ALDHI
ALDH-E2
Target ALDH2
Molecular Weight(MW) 56.3 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using ALDH2 antibody [4G6A3].

Application

WB analysis of human ALDH2 recombinant protein using ALDH2 antibody [4G6A3].

Application

WB analysis of (1) HepG2, (2) A549, (3) rat live, (4) mouse liver and (5) mouse brain lysates using ALDH2 antibody [4G6A3].

Application

WB analysis of lysates from (1) untransfected and (2) ALDH2 (a.a. 317-517)-hIgGFc transfected HEK293 cells using ALDH2 antibody [4G6A3].

Application

IHC-P analysis of rectum cancer tissues using ALDH2 antibody [4G6A3].

Application

IHC-P analysis of cervical cancer tissues using ALDH2 antibody [4G6A3].

Application

FACS analysis of HeLa cells using ALDH2 antibody [4G6A3] (green) or a negative control (red).

Application

ICC/IF analysis of HepG2 cells using ALDH2 antibody [4G6A3] (green) and DRAQ5 fluorescent DNA dye (blue).
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
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