Rabbit Polyclonal antibody to alpha 2 Macroglobulin (alpha-2-macroglobulin)Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human alpha 2 Macroglobulin. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CPAMD5 antibody DKFZp779B086 antibody S863-7 antibody A2M antibody alpha-2-macroglobulin antibody alpha-2-M antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
Molecular Weight(MW)
163 kDa (note)
Cellular Localization
Secreted
Application
Application
Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE diluted at 1:1000
Application
Human tissue extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with alpha 2 Macroglobulin antibody [N2N3] diluted at 1:10000.
Positive Control
293T , A431 , Jurkat , human plasma
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.