Application
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Alpha-2C adrenergic receptor antibody diluted at 1:1000Application
Immunohistochemical analysis of paraffin-embedded ES2 xenograft, using alpha 2c Adrenergic Receptor antibody at 1:100 dilution.| Product Name | alpha 2c Adrenergic Receptor antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to alpha 2c Adrenergic Receptor (adrenergic, alpha-2C-, receptor)Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 2c Adrenergic Receptor. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (100%), Rat (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ADRA2L2 antibody ADRA2RL2 antibody ADRARL2 antibody ALPHA2CAR antibody ADRA2C antibody alpha-2C adrenoceptor antibody alpha-2C adrenoreceptor antibody alpha-2C-adrenergic receptor antibody alpha-2CAR antibody alpha-2 adrenergic receptor subtype C4 |
|---|---|
| Molecular Weight(MW) | 50 kDa (note) |
| Cellular Localization | Cell membrane |
Application
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Alpha-2C adrenergic receptor antibody diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded ES2 xenograft, using alpha 2c Adrenergic Receptor antibody at 1:100 dilution.| Positive Control | HeLa , HepG2 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
