Rabbit Polyclonal antibody to alpha Adducin (phospho Ser726)This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq]
Modification
p-Ser726
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
Suggested starting dilutions are as follows. WB: 1:500-1:1000,IHC: 1:50-1:100,ICC/IF: 1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CRE-BP1 CREB2 HB16 MGC111558 TREB7
Target
alpha Adducin (phospho Ser726)
Application Notes
Suggested starting dilutions are as follows. WB: 1:500-1:1000,IHC: 1:50-1:100,ICC/IF: 1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.