| Product Name | Alpha fetoprotein / AFP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to alpha FetoproteinThis is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
| Immunogen | Full length protein (Human cord blood). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. Pairs with most alpha Fetoprotein monoclonal antibodies. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HPAFP 174 FETA 104150 alpha Fetoprotein AFP P02771 |
|---|---|
| Target | alpha Fetoprotein |
| Tissue Specificity | Recognises Human alpha Fetoprotein. No cross reactivity was detected with human Albumin, CEA, Ferritin, hCG, PAP, PSA, CA125, CA 15 3, or CA 19 9. |
| Cellular Localization | Cytoplasmic |
| Application Notes | ELISA: Use at an assay dependent dilution. Pairs with most alpha Fetoprotein monoclonal antibodies. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide. Constituents: 0.85% Sodium chloride, 0.015M Potassium phosphate. pH 7.4 |
