| Product Name | alpha Lactalbumin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [0.N.14] to alpha Lactalbuminalpha Lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. alpha Lactalbumin is a potent Ca 2+ -elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric alpha Lactalbumin killed all transformed, embryonic, and lymphoid cells tested but spared mature epithelial elements. It suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. alpha Lactalbumin may be helpful in ascertaining the site of origin of metastatic breast tumors. |
| Immunogen | Full length native protein (purified casein and alpha lactalbumin) (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 0.N.14 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FWB |
| For IHC-Fr (Acetone-fixed tissue only): Use at an assay dependent dilution. . For WB: Use at a concentration of 1 μg/ml. Detects a band of approximately 14 kDa. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | 3906 MGC138521 alpha Lactalbumin P00709 LALBA 149750 MGC138523 |
|---|---|
| Target | alpha Lactalbumin |
| Tissue Specificity | Recognizes human alpha lactalbumin (a-LA) at 14kD |
| Cellular Localization | Cytoplasmic |
| Positive Control | Breast Carcinomas |
|---|---|
| Application Notes | For IHC-Fr (Acetone-fixed tissue only): Use at an assay dependent dilution. . For WB: Use at a concentration of 1 μg/ml. Detects a band of approximately 14 kDa. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC - Do not freeze |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4, containing 0.2% BSA and 0.09% sodium azide |
