Rabbit polyclonal antibody to AMIGO1 (adhesion molecule with Ig-like domain 1)Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
Immunogen
Recombinant protein encompassing a sequence within the center region of human AMIGO1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Rhesus Monkey, BovineMouse (89%), Rat (86%), Rhesus Monkey (100%), Bovine (97%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
AMIGO antibody, AMIGO-1 antibody, AMIGO1 antibody, amphoterin-induced gene and ORF antibody, amphoterin-induced protein 1 antibody, alivin-2 antibody, adhesion molecule with Ig-like domain 1 antibody
Target
AMIGO1
Molecular Weight(MW)
55 kDa (note) (2)
Cellular Localization
Membrane; Single-pass type I membrane protein , Cell projection , axon , Membrane , Cell projection , axon
Application
Application
Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.