Rabbit polyclonal antibody to AmphiregulinThe protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq, Jul 2008]
Immunogen
Synthetic peptide sequence corresponding to amino acids 8 – 26 of Human amphiregulin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PIP
Immunohistology - Paraffin: Min Dilution 10 ug/ml Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human
Predicted Reactivity
Mouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CRDGF , AREG , amphiregulin , AR , SDGF
Target
Amphiregulin
Tissue Specificity
This antibody recognizes human Amphiregulin.
Application
Application
IHC-P analysis of human adrenal gland tissue using Amphiregulin antibody.
Application Notes
Immunohistology - Paraffin: Min Dilution 10 ug/ml Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.