Application
Sample (30 ug of whole cell lysate) A: Raji 15% SDS PAGE diluted at 1:1000Application
Amylin antibody [N2C3] detects Amylin protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Amylin antibody [N2C3] dilution: 1:250.| Product Name | Amylin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Amylin (islet amyloid polypeptide)Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Amylin. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | BovineBovine (81%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DAP antibody, IAP antibody, IAPP antibody, diabetes-associated peptide antibody, amylin antibody, Islet amyloid polypeptide (diabetes-associated peptide, amylin) antibody, islet amyloid polypeptide antibody, insulinoma amyloid peptide antibody |
|---|---|
| Target | Amylin |
| Molecular Weight(MW) | 10 kDa (note) (2) |
| Cellular Localization | Secreted |
Application
Sample (30 ug of whole cell lysate) A: Raji 15% SDS PAGE diluted at 1:1000
Application
Amylin antibody [N2C3] detects Amylin protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Amylin antibody [N2C3] dilution: 1:250.| Positive Control | Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
