Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE ARP4 antibody diluted at 1:1000| Product Name | Angiopoietin-like 4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Angiopoietin-like 4This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Angiopoietin-like 4. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Pig, Sheep, BovinePig (83%), Sheep (83%), Bovine (83%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ANGPTL2 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, ANGPTL4 antibody, angiopoietin-related protein 4 antibody, hepatic fibrinogen/angiopoietin-related protein antibody, PPARG angiopoietin |
|---|---|
| Target | ANGPTL4 |
| Molecular Weight(MW) | 45 kDa (note) (2) |
| Cellular Localization | Secreted , extracellular space , extracellular matrix |
Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE ARP4 antibody diluted at 1:1000| Positive Control | A431 , H1299 , HeLa , HepG2 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
