| Product Name | Annexin II antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Annexin IIThe Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Synthetic peptide: KLSLEGDHST PPSAYGSVKA YT conjugated to KLH, corresponding to N terminal amino acids 9 - 30 of Human Annexin II. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1/1000. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseDogRatBovine |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | P36 LPC2D Annexin II ANXA2 ANX2L4 151740 ANX2 PAP-IV CAL1H PAPIV P07355 LIP2 LPC2 302 PAP IV |
|---|---|
| Target | Annexin II |
| Cellular Localization | Cell Membrane |
| Positive Control | Bovine lung crude membrane binding annexin fraction. |
|---|---|
| Application Notes | WB: 1/1000. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% sodium azide; Constituents: 20mM Tris HCl, 150mM Sodium chloride. pH 7.5 |
