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Antithrombin III antibody, C-term

Catalog Number:OM239621
OM239621
Discount Price
OM239621-100ul
1~2 Week
100ul
OM239621-50ul
50ul
OM239621-20ul
20ul
1~2 Week
Product Profile
Product Name Antithrombin III antibody, C-term
Antibody Type Primary Antibodies
Product description Rabbit polyclonal to Antithrombin III (C-term)The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 12 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq]
Immunogen KLH conjugated synthetic peptide between 371~401 amino acids from the C-terminal region of human SERPINC1.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications FACSICC/IFIHC-PWB
ELISA: Use at 1:1,000
Species Reactivity HumanMouse
Concentration 0.2mg/ml
Purification Unpurified
Target Information
Gene Synonyms ATIII, PRO0309, AntithrombinIII, Antithrombin-III, SERPINC1, AT3, Antithrombin III
Target SERPINC1
Molecular Weight(MW) 52.602 kDa (note)
Application

Application

Western blot analysis of SERPINC1 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). SERPINC1 (arrow) was detected using the purified Pab.

Application

SERPINC1 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Confocal immunofluorescent analysis of SERPINC1 Antibody (C-term) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Application

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINC1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes ELISA: Use at 1:1,000
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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