Rabbit polyclonal antibody to AP2M1This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human AP2M1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
adaptor-related protein complex 2, mu 1 subunit , mu2 , CLAPM1 , AP50
Target
AP2M1
Molecular Weight(MW)
49 kDa (note)
Application
Application
WB analysis of extracts from various cell lines using AP2M1 antibody.
Application
IHC-P analysis of rat kidney using AP2M1 antibody at a dilution of 1:100.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.