Application
Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 μg/mL.Application
Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Product Name | APBA1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to APBA1The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008] |
| Immunogen | APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| WB: 0.5 ug/ml. IF: 20 ug/ml | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | amyloid beta (A4) precursor protein-binding, family A, member 1 , MINT1 , X11ALPHA , X11 , LIN10 , D9S411E , X11A |
|---|---|
| Target | APBA1 |
| Tissue Specificity | At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins. |
Application
Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 μg/mL.
Application
Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Application Notes | WB: 0.5 ug/ml. IF: 20 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stored At 4ºc For Three Months And -20ºc, Stable For Up To One Year. As With All Antibodies Care Should Be Taken To Avoid Repeated Freeze Thaw Cycles. Antibodies Should Not Be Exposed To Prolonged High Temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
