Application
Immunohistochemistry of APBA2 in human brain tissue with APBA2 antibody at 10 μg/mL.Application
Western blot analysis of APBA2 in human brain tissue lysate with APBA2 antibody at (A) 1 and (B) 2 ug/ml.Application
Immunofluorescence of APBA2 in human brain tissue with APBA2 antibody at 20 μg/mL.| Product Name | APBA2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to APBA2APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Amyloid beta A4 proteinbinding family A member 2, X11L, APBA2, Amyloid beta A4 proteinbinding family A member2, X11beta, MINT2, Amyloid beta A4 protein-binding family A member 2, LIN10 |
|---|---|
| Target | APBA2 |
| Tissue Specificity | This antibody is specific for APBA2 |
Application
Immunohistochemistry of APBA2 in human brain tissue with APBA2 antibody at 10 μg/mL.
Application
Western blot analysis of APBA2 in human brain tissue lysate with APBA2 antibody at (A) 1 and (B) 2 ug/ml.
Application
Immunofluorescence of APBA2 in human brain tissue with APBA2 antibody at 20 μg/mL.| Positive Control | Blocking Peptide: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
