Application
Immunofluorescence of APC7 in rat kidney tissue with APC7 antibody at 20 ug/ml.Application
Western blot analysis of APC7 in rat kidney tissue lysate with APC7 antibody at (A) 1 and (B) 2 ug/ml.| Product Name | APC7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to APC7Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ANAPC7, Anaphase promoting complex 7, APC7, Anaphase promoting complex7 |
|---|---|
| Target | APC7 |
| Tissue Specificity | This antibody is specific for APC7 |
Application
Immunofluorescence of APC7 in rat kidney tissue with APC7 antibody at 20 ug/ml.
Application
Western blot analysis of APC7 in rat kidney tissue lysate with APC7 antibody at (A) 1 and (B) 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85187-PEP - APC7 Peptide Lysates: Cat. No. GTX27944 - Rat Kidney Tissue Lysate |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
