Application
Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with APH1A antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Product Name | APH1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to APH1AAPH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198).[supplied by OMIM] |
| Immunogen | Synthetic peptide - KLH conjugated |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB (0.5 - 1 µg/ml), IHC-P (5 µg/ml) | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 6530402N02Rik, APH-1, APH-1A, CGI-78, APH 1, APH 1A, CGI 78, APH1, CGI78 |
|---|---|
| Tissue Specificity | 18 amino acid peptide from near the center of human APH1a. |
Application
Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with APH1A antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Application Notes | WB (0.5 - 1 µg/ml), IHC-P (5 µg/ml) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Storage Buffer | PBS, 0.02% sodium azide. |
