Application
Western blot analysis of extracts of various cell lines, using APLP2 antibody.Application
Immunofluorescence analysis of U20S cell using APLP2 antibody. Blue: DAPI for nuclear staining.Application
Immunohistochemistry of paraffin-embedded human kidney using APLP2 antibody at dilution of 1:200 (x400 lens)| Product Name | APLP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to APLP2This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Immunogen | Recombinant protein of human APLP2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PIPWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:20 - 1:50 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | amyloid beta precursor like protein 2 , APPH , APPL2 , CDEBP |
|---|---|
| Target | APLP2 |
Application
Western blot analysis of extracts of various cell lines, using APLP2 antibody.
Application
Immunofluorescence analysis of U20S cell using APLP2 antibody. Blue: DAPI for nuclear staining.
Application
Immunohistochemistry of paraffin-embedded human kidney using APLP2 antibody at dilution of 1:200 (x400 lens)| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:20 - 1:50 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
