Rabbit polyclonal antibody to Apolipoprotein A1Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
Immunogen
Purified mouse apolipoprotein AI from pooled mouse plasma high density lipoprotein.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISARIDWB
ELISA: Use at an assay dependent dilution. RID: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa. Optimal dilutions/concentrations should be determined by the end user.
Species Reactivity
MouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
ELISA: Use at an assay dependent dilution. RID: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa. Optimal dilutions/concentrations should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.