| Product Name | Apolipoprotein A1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Apolipoprotein A1Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. |
| Immunogen | Full length native protein (purified from plasma high density lipoprotein) (Hamster). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | DIDRIDWB |
| DID: Use at an assay dependent dilution. RID: 1/200. WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Hamster |
| Concentration | 1mg/ml |
| Gene Synonyms | APOA1/APOC3 fusion gene, Apo AI, APOA1, Apolipoprotein A I precursor, Apolipoprotein of high density lipoprotein |
|---|---|
| Target | Apolipoprotein A1 |
| Cellular Localization | Secreted |
| Application Notes | DID: Use at an assay dependent dilution. RID: 1/200. WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide. Constituents: 100U/ml Penicillin, 10ug/ml Streptomycin, 25ng/ml Amphotericin B. |
